(S,R,S)-AHPC-C7-amine hydrochloride is a novel E3 ligase ligand-linker conjugate that combines a VH032-derived VHL ligand with a C7 linker for targeted protein degradation. Its design facilitates the development of PROTACs targeting estrogen-related receptor α (ERRα), highlighting its utility in research on protein modulation and degradation pathways. This compound serves as a valuable tool in the study of E3 ligase-mediated degradation mechanisms and therapeutic applications in cancer and other diseases.
(S,R,S)-AHPC-C7-amine hydrochloride is a novel E3 ligase ligand-linker conjugate that combines a VH032-derived VHL ligand with a C7 linker for targeted protein degradation. Its design facilitates the development of PROTACs targeting estrogen-related receptor α (ERRα), highlighting its utility in research on protein modulation and degradation pathways. This compound serves as a valuable tool in the study of E3 ligase-mediated degradation mechanisms and therapeutic applications in cancer and other diseases.
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