(S,R,S)-AHPC-C8-NH2 hydrochloride

Catalog No.: A80019
E3 Ligase Ligand-Linker Conjugate
(S,R,S)-AHPC-C8-NH2 hydrochloride is an E3 ligase ligand-linker conjugate designed for use in PROTAC technology. It features a VH032-derived VHL ligand, facilitating the targeted degradation of proteins through the ubiquitin-proteasome system. This compound is suited for applications in chemical biology and drug discovery, enabling researchers to investigate cellular pathways and protein interactions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-AHPC-C8-NH2 hydrochloride is an E3 ligase ligand-linker conjugate designed for use in PROTAC technology. It features a VH032-derived VHL ligand, facilitating the targeted degradation of proteins through the ubiquitin-proteasome system. This compound is suited for applications in chemical biology and drug discovery, enabling researchers to investigate cellular pathways and protein interactions.
Product Information
Catalog NumA80019
FormulaC31H48ClN5O4S
Molecular Weight622.26
CAS Number2376139-49-8
SMILES[H]Cl.O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCCCN)=O
SynonymsVH032-C8-NH2 hydrochloride
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This equation is commonly abbreviated as: C1V1 = C2V2

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