(S,R,S)-AHPC-CO-C-piperazine

Catalog No.: A80088
E3 Ligase Ligand-Linker Conjugates
(S,R,S)-AHPC-CO-C-piperazine is a ligand-linker conjugate targeting E3 ligases. This compound facilitates the formation of protein ubiquitination complexes, making it valuable for studying protein degradation pathways and developing targeted protein degradation therapies. Its unique structure enables specific interactions with E3 ligases, providing insights into their role in various cellular processes. This reagent is instrumental in chemical biology and drug discovery applications focused on modulating ubiquitin-proteasome system functions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-AHPC-CO-C-piperazine is a ligand-linker conjugate targeting E3 ligases. This compound facilitates the formation of protein ubiquitination complexes, making it valuable for studying protein degradation pathways and developing targeted protein degradation therapies. Its unique structure enables specific interactions with E3 ligases, providing insights into their role in various cellular processes. This reagent is instrumental in chemical biology and drug discovery applications focused on modulating ubiquitin-proteasome system functions.
Product Information
Catalog NumA80088
FormulaC28H40N6O4S
Molecular Weight556.72
CAS Number2940856-78-8
SMILESC([C@@H](NC(CN1CCNCC1)=O)C(C)(C)C)(=O)N2[C@H](C(NCC3=CC=C(C=C3)C4=C(C)N=CS4)=O)C[C@@H](O)C2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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