(S,R,S)-AHPC-PEG1-NH2 dihydrochloride

Catalog No.: A80072
E3 Ligase Ligand-Linker Conjugate
(S,R,S)-AHPC-PEG1-NH2 dihydrochloride is an E3 ligase ligand-linker conjugate featuring a VHL ligand designed for the ubiquitin-proteasome system, combined with a PROTAC linker. This compound is instrumental in the development of PROTACs, facilitating targeted protein degradation and elucidating cellular processes. Its utility extends to studies exploring protein interactions and degradation pathways, making it a valuable tool in chemical biology and drug discovery research.
Grouped product items
Size Price Stock Qty
5mg
$140.00
In stock
10mg
$230.00
In stock
25mg
$415.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-AHPC-PEG1-NH2 dihydrochloride is an E3 ligase ligand-linker conjugate featuring a VHL ligand designed for the ubiquitin-proteasome system, combined with a PROTAC linker. This compound is instrumental in the development of PROTACs, facilitating targeted protein degradation and elucidating cellular processes. Its utility extends to studies exploring protein interactions and degradation pathways, making it a valuable tool in chemical biology and drug discovery research.
Product Information
Catalog NumA80072
FormulaC26H39Cl2N5O5S
Molecular Weight604.59
CAS Number2341796-83-4
SMILESO=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCN)=O.Cl.Cl
SynonymsVH032-PEG1-NH2 dihydrochloride
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2