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Biological Activity
(S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.14 mL | 80.68 mL | 161.35 mL |
| 0.5 mM | 3.23 mL | 16.14 mL | 32.27 mL |
| 1 mM | 1.61 mL | 8.07 mL | 16.14 mL |
| 5 mM | 0.32 mL | 1.61 mL | 3.23 mL |
*The above data is based on the productmolecular weight 619.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21660 |
|---|---|
| CAS No. | 2010159-56-3 |
| Formula | C30H45N5O7S |
| M. Wt | 619.77 |
| Purity | >98% |
| Synonyms | VH032-PEG3-NH2; VHL Ligand-Linker Conjugates 1; E3 ligase Ligand-Linker Conjugates 5 Free Base |
| SMILES | O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCN)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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