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(S,R,S)-AHPC-PEG3-propionic acid

Catalog No.: A80015
E3 ligase ligand-Linker Conjugate
(S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate designed for use in PROTAC technology. It features the (S,R,S)-AHPC-based VHL ligand along with a three-unit PEG linker that facilitates the targeted degradation of proteins. This compound is essential for studying E3 ligase activity and its applications in targeted protein modulation research.
(S,R,S)-AHPC-PEG3-propionic acid 2140807-42-5 E3 ligase ligand-Linker Conjugate
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25mg
$485.00
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-AHPC-PEG3-propionic acid is a synthesized E3 ligase ligand-linker conjugate designed for use in PROTAC technology. It features the (S,R,S)-AHPC-based VHL ligand along with a three-unit PEG linker that facilitates the targeted degradation of proteins. This compound is essential for studying E3 ligase activity and its applications in targeted protein modulation research.
Product Information
Catalog NumA80015
FormulaC32H46N4O9S
Molecular Weight662.79
CAS Number2140807-42-5
SMILESO=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCOCCOCCC(O)=O)=O)=O)C[C@H](O)C3
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PROTAC > E3 Ligase Ligand-Linker Conjugate