(S,R,S)-AHPC-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that utilizes the (S,R,S)-AHPC derived VHL ligand in conjunction with a five-unit PEG linker. This compound is primarily designed for use in PROTAC (Proteolysis Targeting Chimeras) technology, facilitating targeted protein degradation. Its key biological activity includes effective binding to E3 ligases, enhancing the recruitment of specific substrates for ubiquitination and subsequent proteasomal degradation. This reagent is valuable for various research applications in the fields of targeted protein modulation and cancer therapeutics.
(S,R,S)-AHPC-PEG5-COOH is a synthesized E3 ligase ligand-linker conjugate that utilizes the (S,R,S)-AHPC derived VHL ligand in conjunction with a five-unit PEG linker. This compound is primarily designed for use in PROTAC (Proteolysis Targeting Chimeras) technology, facilitating targeted protein degradation. Its key biological activity includes effective binding to E3 ligases, enhancing the recruitment of specific substrates for ubiquitination and subsequent proteasomal degradation. This reagent is valuable for various research applications in the fields of targeted protein modulation and cancer therapeutics.
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