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(S,R,S)-CO-C2-acid

Catalog No.: A80007
E3 Ligase Ligand-Linker Conjugates
(S,R,S)-CO-C2-acid is a functionalized von-Hippel-Lindau (VHL) protein ligand designed for use in E3 ligase ligand-linker conjugates. This compound enables the development of proteolysis-targeting chimeras (PROTACs) by facilitating the conjugation of target protein ligands. Its application enhances the targeted degradation of specific proteins, making it a valuable tool in the field of targeted protein modulation and therapeutic development.
(S,R,S)-CO-C2-acid 2172819-72-4 E3 Ligase Ligand-Linker Conjugates
Grouped product items
Size Price Stock Qty
5mg
$40.00
In stock
10mg
$60.00
In stock
25mg
$100.00
In stock
50mg
$150.00
In stock
100mg
$215.00
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Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(S,R,S)-CO-C2-acid is a functionalized von-Hippel-Lindau (VHL) protein ligand designed for use in E3 ligase ligand-linker conjugates. This compound enables the development of proteolysis-targeting chimeras (PROTACs) by facilitating the conjugation of target protein ligands. Its application enhances the targeted degradation of specific proteins, making it a valuable tool in the field of targeted protein modulation and therapeutic development.
Product Information
Catalog NumA80007
FormulaC26H34N4O6S
Molecular Weight530.64
CAS Number2172819-72-4
SMILESOC(CCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O)=O
SynonymsVH 032 amide-alkylC2-acid
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

PROTAC > E3 Ligase Ligand-Linker Conjugate