S107

Catalog No.: A12716

S107

S107 Chemical Structure

CAS NO. 927871-76-9

S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.

Availability: In stock

Package Price Qty
5 mg
$110.00
10 mg
$170.00
50 mg
$520.00
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Biological Activity

S107 is a RyR-selective 1,4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
In vitro DMSO 40 mg/mL (191.1 mM)
Water Insoluble
Ethanol 40 mg/mL (191.1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 47.78 mL 238.88 mL 477.76 mL
0.5 mM 9.56 mL 47.78 mL 95.55 mL
1 mM 4.78 mL 23.89 mL 47.78 mL
5 mM 0.96 mL 4.78 mL 9.56 mL

*The above data is based on the productmolecular weight 209.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12716
CAS No. 927871-76-9
Formula C11H15NOS
M. Wt 209.31
Purity >98%
SMILES COC1=CC=C2C(CN(C)CCS2)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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