SA57 is a selective inhibitor of fatty acid amide hydrolase (FAAH), exhibiting IC50 values of 3.2 nM and 1.9 nM for mouse and human FAAH, respectively. In addition to its primary target, SA57 demonstrates inhibitory effects on 2-arachidonoylglycerol hydrolases, including monoacylglycerol lipase (MAGL) with IC50s of 410 nM and 1.4 μM for mouse and human, as well as mouse α/β-hydrolase domain-containing protein 6 (mABHD6) with an IC50 of 850 nM. This compound is valuable for research related to the endocannabinoid system and pain management studies.
SA57 is a selective inhibitor of fatty acid amide hydrolase (FAAH), exhibiting IC50 values of 3.2 nM and 1.9 nM for mouse and human FAAH, respectively. In addition to its primary target, SA57 demonstrates inhibitory effects on 2-arachidonoylglycerol hydrolases, including monoacylglycerol lipase (MAGL) with IC50s of 410 nM and 1.4 μM for mouse and human, as well as mouse α/β-hydrolase domain-containing protein 6 (mABHD6) with an IC50 of 850 nM. This compound is valuable for research related to the endocannabinoid system and pain management studies.
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