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|Storage||at -20°C 3 years Powder|
|Synonyms||FCE-28073(R-isomer), PNU-151774E, NW-1015|
|SMILES code||C[[email protected]@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O|
|Safinamide Mesylate is mesylate salt of Safinamide, which selectively and reversibly inhibits MAO-B with IC50 of 0.45 μM.|
|Solubility (25°C) *||In vitro||DMSO||80 mg/mL (200.77 mM)|
|Water||80 mg/mL (200.77 mM)|
|Ethanol||13 mg/mL (32.62 mM)|
|In vivo||Saline||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||25.09 mL||125.47 mL||250.94mL|
|0.5 mM||5.02 mL||25.09 mL||50.19 mL|
|1 mM||2.51 mL||12.55 mL||25.09 mL|
|5 mM||0.5 mL||2.51 mL||5.02 mL|
*The above data is based on the productmolecular weight 398.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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