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Safinamide Mesylate is mesylate salt of Safinamide, which selectively and reversibly inhibits MAO-B with IC50 of 0.45 μM.
Targets
| MAO-B | MAO-A | |||
| 98 nM | 580 μM |
| In vitro (25°C) | DMSO | 80 mg/mL (200.77 mM) | |
| Water | 80 mg/mL (200.77 mM) | ||
| Ethanol | 13 mg/mL (32.62 mM) | ||
| In vivo | Saline | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.09 mL | 125.47 mL | 250.94 mL |
| 0.5 mM | 5.02 mL | 25.09 mL | 50.19 mL |
| 1 mM | 2.51 mL | 12.55 mL | 25.09 mL |
| 5 mM | 0.5 mL | 2.51 mL | 5.02 mL |
*The above data is based on the productmolecular weight 398.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10818 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 398.5 |
| Formula | C17H19FN2O2.CH4O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 202825-46-5 |
| Synonyms | FCE-28073(R-isomer), PNU-151774E, NW-1015 |
| SMILES | C[[email protected]@H](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O |
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