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Saikosaponin bk1

Catalog No.: A76915
NOX5 Dehydrogenase Domain Binder
Saikosaponin bk1 is a specific binder for the dehydrogenase domain of NADPH oxidase 5 (NOX5), exhibiting hepatoprotective properties. It forms stable interactions with the NOX5 enzyme derived from Cylindrospermum stagnale, making it a valuable tool in studies of oxidative stress. This compound is particularly relevant in research focused on COVID-19 and alcoholic liver injury, contributing to the understanding of these conditions at a molecular level.
Saikosaponin bk1 110352-77-7 NOX5 Dehydrogenase Domain Binder
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSaikosaponin bk1 is a specific binder for the dehydrogenase domain of NADPH oxidase 5 (NOX5), exhibiting hepatoprotective properties. It forms stable interactions with the NOX5 enzyme derived from Cylindrospermum stagnale, making it a valuable tool in studies of oxidative stress. This compound is particularly relevant in research focused on COVID-19 and alcoholic liver injury, contributing to the understanding of these conditions at a molecular level.
Product Information
Catalog NumA76915
FormulaC48H78O17
Molecular Weight927.12
CAS Number110352-77-7
SMILESC[C@]12C(C=C[C@@]3([H])[C@]2(CC[C@]4([H])[C@@]3(CC[C@@H](C4(C)C)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O[C@H]6[C@@H]([C@@H]([C@H]([C@@H](O6)C)O)O)O)CO[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)C)C)=C8[C@@]([C@@H](C1)O)(CCC(C)(C8)C)CO
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Immunology & Inflammation > NADPH oxidase