SB 218078

Catalog No.: A15480

Chk1 Inhibitor

SB 218078

SB 218078 Chemical Structure

CAS NO. 135897-06-2

SB 218078 is an inhibitor of checkpoint kinase 1 (Chk1) that displays selectivity over other protein kinases (IC50 values are 15, 250 and 1000 nM for Chk1, cdc2 and PKC respectively)

Availability: In stock

Package Price Qty
2 mg

Regular Price: $100.00

Special Price $90.00

5 mg

Regular Price: $200.00

Special Price $180.00

10 mg

Regular Price: $320.00

Special Price $288.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SB 218078 is an inhibitor of checkpoint kinase 1 (Chk1) that displays selectivity over other protein kinases (IC50 values are 15, 250 and 1000 nM for Chk1, cdc2 and PKC respectively)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.42 mL 127.1 mL 254.2 mL
0.5 mM 5.08 mL 25.42 mL 50.84 mL
1 mM 2.54 mL 12.71 mL 25.42 mL
5 mM 0.51 mL 2.54 mL 5.08 mL

*The above data is based on the productmolecular weight 393.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15480
Actions Inhibitor
M. Wt 393.39
Formula C24H15N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 135897-06-2
Synonyms SB218078, SB-218078
SMILES C1CC2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C1O2)C7=C53)C(=O)NC6=O

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