Fig. 1 · Structure

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SB 258741

5-HT7 Antagonist

SB 258741 is a selective antagonist of the 5-HT7 receptor, exhibiting a high affinity with a pKi of 8. This compound has demonstrated significant potential in studying serotonin-related pathways, making it valuable for research focused on mood disorders and other neuropsychiatric conditions. Its specificity for the 5-HT7 receptor allows for targeted investigations into receptor signaling and therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 201038-58-6
Applications 5-HT7 Antagonist
Formula C19H30N2O2S
Molecular Weight 350.52
SMILES
O=S(N1[C@@H](CCN2CCC(C)CC2)CCC1)(C3=CC=CC(C)=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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