SB-334867 free base is a selective non-peptide orexin OX1 receptor antagonist with a pKb value of 7.2.
Targets
Target
Value
Product Information
Catalog Num
A16695
Formula
C17H13N5O2
Molecular Weight
319.32
CAS Number
792173-99-0
SMILES
O=C(NC1=CC(OC(C)=N2)=C2C=C1)NC3=CC=NC4=CC=CN=C43
Synonyms
SB334867A free base
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
59 mg/mL (184.76 mM)
Water
Insoluble
Ethanol
Warmed: 3 mg/mL (9.39 mM)
In vivo
1% CMC Na
28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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