SB 399885 HCl

Catalog No.: A14102

5-HT6 antagonist

SB 399885 HCl

SB 399885 HCl Chemical Structure

CAS NO. 402713-80-8

SB 399885 hydrochloride is a potent, brain penetrant, and orally active SR-6 antagonist. It displays > 200-fold selectivity for SR-6 over other serotonin receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human SR-6 receptors, respectively).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $120.00

Special Price $108.00

25 mg

Regular Price: $250.00

Special Price $225.00

50 mg

Regular Price: $400.00

Special Price $360.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SB 399885 hydrochloride is a potent, brain penetrant, and orally active SR-6 antagonist. It displays > 200-fold selectivity for SR-6 over other serotonin receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human SR-6 receptors, respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.4 mL 112.02 mL 224.04 mL
0.5 mM 4.48 mL 22.4 mL 44.81 mL
1 mM 2.24 mL 11.2 mL 22.4 mL
5 mM 0.45 mL 2.24 mL 4.48 mL

*The above data is based on the productmolecular weight 446.353. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14102
Actions Antagonist
M. Wt 446.353
Formula C18H21Cl2N3O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 402713-80-8
Synonyms SB399885, SB-399885
SMILES COC1=C(C=C(C=C1)S(=O)(=O)NC2=CC(=CC(=C2OC)Cl)Cl)N3CCNCC3.Cl

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