Documents & Downloads

SB-656104

5-HT Receptor Antagonist

SB-656104 is a potent antagonist of the 5-HT7 receptor, exhibiting a pKi of 8.70. It effectively inhibits 5-carboxamidotryptamine (5-CT)-stimulated adenylyl cyclase activity, thereby modulating serotonergic signaling pathways. This compound is valuable for research investigations into the role of 5-HT7 receptors in neuropsychiatric disorders and related pharmacological studies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	446020-51-5
Applications	5-HT Receptor Antagonist
Formula	C₂₅H₃₀ClN₃O₃S
Molecular Weight	488.04
SMILES	O=S(N1[C@H](CCC1)CCN2CCC(CC2)OC3=CC=C(C=C3)Cl)(C4=CC=C(C=CN5)C5=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.