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Publications citing Adooq Products
Chemical Information
| Catalog Num | A15233 |
|---|---|
| Actions | Antagonist |
| M. Wt | 448.51 |
| Formula | C24H21FN4O2S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 483313-22-0 |
| Synonyms | SB 674042, SB674042 |
| SMILES | CC1=NC(=C(S1)C2=CC=CC=C2F)C(=O)N3CCCC3CC4=NN=C(O4)C5=CC=CC=C5 |
Description |
SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.3 mL | 111.48 mL | 222.96mL |
| 0.5 mM | 4.46 mL | 22.3 mL | 44.59 mL |
| 1 mM | 2.23 mL | 11.15 mL | 22.3 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
*The above data is based on the productmolecular weight 448.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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