Signaling Pathway
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| Discription | SB590885 is a selective small-molecule inhibitor of the B-Raf kinase and Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively. | ||
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| Catalog Num | A10829 |
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| Formula | C27H27N5O2 |
| Molecular Weight | 453.5 |
| CAS Number | 405554-55-4 |
| SMILES | CN(C)CCOC1=CC=C(C=C1)C2=N/C(=C\3/C=CC4=C(CCC4=C3)N=O)/C(=C5C=CNC=C5)N2 |
| Synonyms | SB-590885 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 5 mg/mL (11.02 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% Cremophor EL, 2% N,N-dimethylacetamide, pH 5.0 | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.05 mL | 110.25 mL | 220.51 mL |
| 0.5 mM | 4.41 mL | 22.05 mL | 44.1 mL |
| 1 mM | 2.21 mL | 11.03 mL | 22.05 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.41 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
