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Biological Activity
SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain?Ccontaining 4 (ARRDC4).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.68 mL | 103.4 mL | 206.81 mL |
| 0.5 mM | 4.14 mL | 20.68 mL | 41.36 mL |
| 1 mM | 2.07 mL | 10.34 mL | 20.68 mL |
| 5 mM | 0.41 mL | 2.07 mL | 4.14 mL |
*The above data is based on the productmolecular weight 483.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18962 |
|---|---|
| CAS No. | 781628-99-7 |
| Formula | C24H25N3O6S |
| M. Wt | 483.54 |
| Purity | >98% |
| Synonyms | SBI477, SBI 477 |
| SMILES | O=C(NC1=NC(C2=CC=C(OC)C=C2)=CS1)C3=CC=C(OCC(N4CCOCC4)=O)C(OC)=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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