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SC-VC-PAB-DM1

Catalog No.: A41449
Drug-Linker Conjugates for ADC
SC-VC-PAB-DM1 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs), employing DM1 (Mertansine), a potent tubulin inhibitor. This conjugate exhibits significant antitumor activity through targeted delivery, facilitating the precise release of the cytotoxic agent in malignant tissues. SC-VC-PAB-DM1 is suitable for research applications focused on cancer therapeutics and the development of effective ADCs.
SC-VC-PAB-DM1 2259318-47-1 Drug-Linker Conjugates for ADC
Grouped product items
Size Price Stock Qty
1mg
$520.00
In stock
5mg
$1,355.00
In stock
10mg
$2,220.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSC-VC-PAB-DM1 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs), employing DM1 (Mertansine), a potent tubulin inhibitor. This conjugate exhibits significant antitumor activity through targeted delivery, facilitating the precise release of the cytotoxic agent in malignant tissues. SC-VC-PAB-DM1 is suitable for research applications focused on cancer therapeutics and the development of effective ADCs.
Product Information
Catalog NumA41449
FormulaC61H82ClN9O19
Molecular Weight1280.81
CAS Number2259318-47-1
SMILESC[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCC(ON6C(CCC6=O)=O)=O)=O)=O)=O)C=C5)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC