SCH 900229 is a selective γ-secretase inhibitor targeting presenilin 1 (PS1) with an Aβ40 IC50 value of 1.3 nM, demonstrating strong efficacy in reducing amyloid-β levels. This compound exhibits significant Aβ-lowering effects following oral administration in preclinical animal models. It has progressed to human clinical trials as a potential therapeutic agent for Alzheimer's disease, highlighting its relevance in neurodegenerative research.
SCH 900229 is a selective γ-secretase inhibitor targeting presenilin 1 (PS1) with an Aβ40 IC50 value of 1.3 nM, demonstrating strong efficacy in reducing amyloid-β levels. This compound exhibits significant Aβ-lowering effects following oral administration in preclinical animal models. It has progressed to human clinical trials as a potential therapeutic agent for Alzheimer's disease, highlighting its relevance in neurodegenerative research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
