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SCH772984

Catalog No.: A12824
ERK Inhibitor
Adooq's SCH772984 has been cited by 6 publications
SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.
SCH772984
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Product Name Price Stock Qty
SCH772984 5mg
Special Price $88.00 Regular Price $110.00
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SCH772984 10mg
Special Price $136.00 Regular Price $170.00
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SCH772984 25mg
Special Price $272.00 Regular Price $340.00
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SCH772984 50mg
Special Price $384.00 Regular Price $480.00
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Adooq Products cited in reputable paper
Adooq's SCH772984 has been cited by 6 publications
  • Yuki Shimizu, .et al. , Cancer Lett, 2022, Sep 1;543 PMID: 35724767
  • Yajun Li, .et al. , Cell Prolif, 2022, Oct;55(10) PMID: 35708050
  • Sergey A. Dyshlovoy, .et al. , Pharmaceuticals, 2021, 14(10), 949
  • Sergey A Dyshlovoy, .et al. , Sci Rep, 2020, Aug 6;10(1):13178 PMID: 32764580
  • Guo X, .et al. , Pflugers Arch, 2018, Jun;470(6):909-921 PMID: 29441404
  • Takuya Hasegawa, .et al. , FEBS Open Bio, 2017, Aug; 7(8): 1154-1165 PMID: 28781955
    • Biological Activity
    Discription SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A12824
    Formula C33H33N9O2
    Molecular Weight 587.68
    CAS Number 942183-80-4
    SMILES C1CN(C[C@@H]1C(=O)NC2=CC3=C(C=C2)NN=C3C4=CC=NC=C4)CC(=O)N5CCN(CC5)C6=CC=C(C=C6)C7=NC=CC=N7
    Synonyms SCH-772984, SCH 772984
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO Warmed: 13 mg/mL (22.12 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+30% PEG 300+ddH2O 0.5 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.02 mL 85.08 mL 170.16 mL
    0.5 mM 3.4 mL 17.02 mL 34.03 mL
    1 mM 1.7 mL 8.51 mL 17.02 mL
    5 mM 0.34 mL 1.7 mL 3.4 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    • Calculator Reset
    MAPK > ERK
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