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SDZ-62-434 free base

Catalog No.: A62945
PAF Antagonist
SDZ-62-434 free base is a potent platelet-activating factor (PAF) antagonist. It exhibits notable antiproliferative activity against various human solid tumors and hematological malignancies. This compound is relevant for research applications focusing on cancer treatment and the modulation of inflammatory responses mediated by PAF.
SDZ-62-434 free base 115621-81-3 PAF Antagonist
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSDZ-62-434 free base is a potent platelet-activating factor (PAF) antagonist. It exhibits notable antiproliferative activity against various human solid tumors and hematological malignancies. This compound is relevant for research applications focusing on cancer treatment and the modulation of inflammatory responses mediated by PAF.
Product Information
Catalog NumA62945
FormulaC23H25N3
Molecular Weight343.46
CAS Number115621-81-3
SMILESC12=C(C=C(C3=CC=C(CN4CCCCC4)C=C3)N5C2=NCC5)C=CC=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Platelet-Activating Factor (PAF) Receptors