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Biological Activity
SDZ-MKS 492 (MKS 492) is a selective type III isozyme inhibitor of cyclic nucleotide phosphodiesterase, effective in allergic bronchoconstriction and platelet activating factor (PAF) or LTB4-induced inflammatory reactions in animals.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.07 mL | 115.35 mL | 230.7 mL |
| 0.5 mM | 4.61 mL | 23.07 mL | 46.14 mL |
| 1 mM | 2.31 mL | 11.54 mL | 23.07 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.61 mL |
*The above data is based on the productmolecular weight 433.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12283 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 114606-56-3 |
| Formula | C20H27N5O6 |
| M. Wt | 433.46 |
| Purity | >98% |
| Synonyms | MKS 492, MKS492, MKS-492 |
| SMILES | O=C(N1C)N(C)C2=C(N(CCOC)C(N[[email protected]](C3=CC=C(OC)C(OC)=C3)CO)=N2)C1=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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