Documents & Downloads

SET-171

Name: SET-171
Brand: Adooq Bioscience
SKU: A40667
Availability: OutOfStock

Cat. No. A40667 CAS 3052985-32-4

INK Inhibitor

SET-171 is a selective JNK (c-Jun N-terminal kinase) inhibitor that demonstrates notable anticancer properties and regulation of lipid metabolism through the suppression of liver pyruvate kinase (PKL) expression. In vitro studies reveal IC50 values of 8.82 μM and 2.97 μM against HepG2 and Huh7 cell lines, respectively, showcasing its potent cytotoxic effects. Furthermore, SET-171 has been shown to significantly decrease triacylglycerol (TAG) levels and inhibit steatosis-related protein expression, highlighting its potential utility in the study of hepatocellular carcinoma (HCC) and non-alcoholic fatty liver disease (NAFLD).

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3052985-32-4
Applications	INK Inhibitor
Formula	C₂₇H₂₁BrN₄O₂S
Molecular Weight	545.45
SMILES	BrC1=CC=CC(NC(CN2CCC3=C(SC(NC(C4=CC=CC5=C4C=CC=C5)=O)=C3C#N)C2)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.