SGC 0946

Catalog No.: A12941

DOT1L inhibitor

SGC 0946

SGC 0946 Chemical Structure

CAS NO.

SGC 0946 is a potent DOT1L methyltransferase inhibitor that blocks H3K79 methylation in A431 cells and MCF10A cells.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $60.00

Special Price $54.00

10 mg

Regular Price: $100.00

Special Price $90.00

25 mg

Regular Price: $200.00

Special Price $180.00

50 mg

Regular Price: $350.00

Special Price $315.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SGC 0946 is a potent DOT1L methyltransferase inhibitor that blocks H3K79 methylation in A431 cells and MCF10A cells.
Targets
DOT1L (Cell-free assay)
0.3 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.17 mL 80.83 mL 161.66 mL
0.5 mM 3.23 mL 16.17 mL 32.33 mL
1 mM 1.62 mL 8.08 mL 16.17 mL
5 mM 0.32 mL 1.62 mL 3.23 mL

*The above data is based on the productmolecular weight 618.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12941
Actions Inhibitor
M. Wt 618.57
Formula C28H40BrN7O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. N/A
Synonyms SGC0946, SGC-0946
SMILES CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[[email protected]@H]2[[email protected]]([[email protected]]([[email protected]@H](O2)N3C(=CC4=C3N=CN=C4N)Br)O)O

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