SGC 707

Catalog No.: A15450

PRMT3 Inhibitor

SGC 707 Chemical Structure

CAS NO. 1687736-54-4

SGC 707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $65.00

Special Price $52.00

25 mg

Regular Price: $140.00

Special Price $112.00

50 mg

Regular Price: $225.00

Special Price $180.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SGC 707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets.
Targets
PRMT3 PRMT3
31 nM53 nM(Kd)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.52 mL 167.62 mL 335.23 mL
0.5 mM 6.7 mL 33.52 mL 67.05 mL
1 mM 3.35 mL 16.76 mL 33.52 mL
5 mM 0.67 mL 3.35 mL 6.7 mL

*The above data is based on the productmolecular weight 298.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15450
Actions Inhibitor
M. Wt 298.3
Formula C16H18N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1687736-54-4
Synonyms SGC707, SGC-707
SMILES C1CCN(C1)C(=O)CNC(=O)NC2=CC3=C(C=C2)C=NC=C3

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