SGLT2-IN-1 is a selective inhibitor of the sodium-dependent glucose cotransporter SGLT2, exhibiting an IC50 of 33 nM in CHO cells transfected with human SGLT2. This compound demonstrates selectivity for SGLT2 over SGLT1, making it a valuable tool for research in glucose homeostasis and metabolic disorders. Additionally, SGLT2-IN-1 serves as an active metabolite of dapagliflozin, contributing to studies focused on diabetes and its associated complications.
SGLT2-IN-1 is a selective inhibitor of the sodium-dependent glucose cotransporter SGLT2, exhibiting an IC50 of 33 nM in CHO cells transfected with human SGLT2. This compound demonstrates selectivity for SGLT2 over SGLT1, making it a valuable tool for research in glucose homeostasis and metabolic disorders. Additionally, SGLT2-IN-1 serves as an active metabolite of dapagliflozin, contributing to studies focused on diabetes and its associated complications.
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