SH-4-54

Catalog No.: A14249

Stat inhibitor

SH-4-54

SH-4-54 Chemical Structure

CAS NO. 1456632-40-8

SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $120.00

Special Price $108.00

10 mg

Regular Price: $200.00

Special Price $180.00

25 mg

Regular Price: $340.00

Special Price $306.00

10mM * 1mL in DMSO

Regular Price: $185.00

Special Price $166.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5.
Targets
STAT3 STAT5
300 nM(Kd)464 nM(Kd)
In vitro DMSO 100 mg/mL (163.77 mM)
Water <1 mg/mL (<1 mM)
Ethanol 79 mg/mL heating (129.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.38 mL 81.89 mL 163.78 mL
0.5 mM 3.28 mL 16.38 mL 32.76 mL
1 mM 1.64 mL 8.19 mL 16.38 mL
5 mM 0.33 mL 1.64 mL 3.28 mL

*The above data is based on the productmolecular weight 610.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14249
Actions Inhibitor
M. Wt 610.59
Formula C29H27F5N2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1456632-40-8
Synonyms SH454
SMILES CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC=C(C=C3)C(=O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F

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