Catalog No.: A14249

Stat inhibitor


SH-4-54 Chemical Structure

CAS NO. 1456632-40-8

SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5.

Availability: In stock

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5 mg
10 mg
25 mg
10mM * 1mL in DMSO
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Biological Activity

SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5.
300 nM(Kd)464 nM(Kd)
In vitro DMSO 94 mg/mL (153.94 mM)
Water Insoluble
Ethanol Warmed: 47 mg/mL (76.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.38 mL 81.89 mL 163.78 mL
0.5 mM 3.28 mL 16.38 mL 32.76 mL
1 mM 1.64 mL 8.19 mL 16.38 mL
5 mM 0.33 mL 1.64 mL 3.28 mL

*The above data is based on the productmolecular weight 610.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14249
Actions Inhibitor
CAS No. 1456632-40-8
Formula C29H27F5N2O5S
M. Wt 610.59
Purity >98%
Synonyms SH454

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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