Biological Activity
SHP394 is an orally efficacious protein tyrosine phosphatase SHP2 inhibitor with an IC50 of 23 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.25 mL | 106.27 mL | 212.54 mL |
0.5 mM | 4.25 mL | 21.25 mL | 42.51 mL |
1 mM | 2.13 mL | 10.63 mL | 21.25 mL |
5 mM | 0.43 mL | 2.13 mL | 4.25 mL |
*The above data is based on the productmolecular weight 470.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18613 |
---|---|
Actions | Inhibitor |
M. Wt | 470.51 |
Formula | C20H25F3N6O2S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2055757-40-7 |
Synonyms | SHP394; SHP-394; SHP 394; |
SMILES | NC1=C(C(N(C)C(N2CCC3(CO[[email protected]@H](C)[[email protected]]3N)CC2)=N1)=O)SC4=C(C(F)(F)F)N=CC=C4 |
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