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Biological Activity
Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. It causes practically no orthostatic hypotension (in contrast to other α1 blockers).
Targets
α1-adrenergic receptor | ||||
In vitro | DMSO | 97 mg/mL (195.74 mM) | |
Water | Insoluble | ||
Ethanol | 97 mg/mL (195.74 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.18 mL | 100.91 mL | 201.82 mL |
0.5 mM | 4.04 mL | 20.18 mL | 40.36 mL |
1 mM | 2.02 mL | 10.09 mL | 20.18 mL |
5 mM | 0.4 mL | 2.02 mL | 4.04 mL |
*The above data is based on the productmolecular weight 495.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10843 |
---|---|
Actions | Antagonist |
CAS No. | 160970-54-7 |
Formula | C25H32F3N3O4 |
M. Wt | 495.5 |
Purity | >98% |
Synonyms | KAD 3213, KMD 3213 |
SMILES | CC(CC1=CC2=C(C(=C1)C(=O)N)N(CC2)CCCO)NCCOC3=CC=CC=C3OCC(F)(F)F |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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