Simotinib is a selective, orally bioavailable inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, with an IC50 value of 19.9 nM. This compound exhibits significant antineoplastic activity, making it a valuable tool for cancer research. Simotinib is primarily utilized in studies investigating the molecular mechanisms of EGFR signaling and the development of targeted therapies for EGFR-dependent tumors.
Simotinib is a selective, orally bioavailable inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, with an IC50 value of 19.9 nM. This compound exhibits significant antineoplastic activity, making it a valuable tool for cancer research. Simotinib is primarily utilized in studies investigating the molecular mechanisms of EGFR signaling and the development of targeted therapies for EGFR-dependent tumors.
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