Sitaxsentan sodium (TBC-11251)

Catalog No.: A11564

ETA receptor antagonist

Sitaxsentan sodium (TBC-11251) Chemical Structure

CAS NO. 210421-74-2

Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$65.00
10 mg
$110.00
25 mg
$220.00
50 mg
$360.00
10mM * 1mL in DMSO
$145.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively.
Targets
ET-A ET-A
0.43 nM(Ki)1.4 nM
In vitro DMSO 40 mg/mL (83.87 mM)
Water <1 mg/mL (<1 mM)
Ethanol 20 mg/mL (41.93 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.97 mL 104.85 mL 209.69 mL
0.5 mM 4.19 mL 20.97 mL 41.94 mL
1 mM 2.1 mL 10.48 mL 20.97 mL
5 mM 0.42 mL 2.1 mL 4.19 mL

*The above data is based on the productmolecular weight 476.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11564
Actions Antagonist
M. Wt 476.89
Formula C18H14ClN2NaO6S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 210421-74-2
Synonyms N/A
SMILES CC1=CC2=C(C=C1CC(=O)C3=C(C=CS3)S(=O)(=O)[N-]C4=C(C(=NO4)C)Cl)OCO2.[Na+]

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Sitaxsentan sodium (TBC-11251) | Sitaxsentan sodium (TBC-11251) Supplier | purchase Sitaxsentan sodium (TBC-11251) | Sitaxsentan sodium (TBC-11251) cost | Sitaxsentan sodium (TBC-11251) manufacturer | order Sitaxsentan sodium (TBC-11251) | Sitaxsentan sodium (TBC-11251) distributor | buy 210421-74-2| 210421-74-2 Supplier | purchase 210421-74-2 | 210421-74-2 cost | 210421-74-2 manufacturer | order 210421-74-2 | 210421-74-2 distributor
Rewards