SJB7

Name: SJB7
Brand: Adooq Bioscience
SKU: A85380
Rating: 5 (288 reviews)

Catalog No.: A85380

PXR Agonist

SJB7 is a potent agonist of the pregnane X receptor (PXR), a key regulator in drug metabolism and excretion. By stabilizing the activation function 2 (AF-2) helix in an "inward" conformation, SJB7 enhances PXR-mediated transcriptional activity. This compound is valuable for research applications involving the study of xenobiotic response and the modulation of metabolic pathways.

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Biological Activity

Description	SJB7 is a potent agonist of the pregnane X receptor (PXR), a key regulator in drug metabolism and excretion. By stabilizing the activation function 2 (AF-2) helix in an "inward" conformation, SJB7 enhances PXR-mediated transcriptional activity. This compound is valuable for research applications involving the study of xenobiotic response and the modulation of metabolic pathways.

Product Information

Catalog Num	A85380
Formula	C22H27N3O4S
Molecular Weight	429.53
CAS Number	2135395-15-0
SMILES	O=S(C1=C(C)N(C2=C(OC)C=C(OC)C(C)=C2)N=N1)(C3=CC=C(C(C)(C)C)C=C3)=O

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