SKF 89976A HCl

Catalog No.: A10849

GABA uptake inhibitor

SKF 89976A HCl

SKF 89976A HCl Chemical Structure

CAS NO. 85375-15-1

SKF 89976A hydrochloride is a potent inhibitor of GABA uptake with IC50 of 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.

Availability: In stock

Package Price Qty
25 mg
$75.00
50 mg
$130.00
100 mg
$220.00
200 mg
$380.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SKF 89976A hydrochloride is a potent inhibitor of GABA uptake with IC50 of 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.89 mL 134.44 mL 268.89 mL
0.5 mM 5.38 mL 26.89 mL 53.78 mL
1 mM 2.69 mL 13.44 mL 26.89 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10849
Actions Inhibitor
CAS No. 85375-15-1
Formula C22H25NO2.HCl
M. Wt 371.9
Solubility DMSO
Purity >98%
SMILES C1CC(CN(C1)CCC=C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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