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Biological Activity
SKF 89976A hydrochloride is a potent inhibitor of GABA uptake with IC50 of 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.89 mL | 134.44 mL | 268.89 mL |
0.5 mM | 5.38 mL | 26.89 mL | 53.78 mL |
1 mM | 2.69 mL | 13.44 mL | 26.89 mL |
5 mM | 0.54 mL | 2.69 mL | 5.38 mL |
*The above data is based on the productmolecular weight 371.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10849 |
---|---|
Actions | Inhibitor |
CAS No. | 85375-15-1 |
Formula | C22H25NO2.HCl |
M. Wt | 371.9 |
Purity | >98% |
SMILES | C1CC(CN(C1)CCC=C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O.Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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