SMS2-IN-3

Name: SMS2-IN-3
Brand: Adooq Bioscience
SKU: A77186
Rating: 5 (288 reviews)

Catalog No.: A77186

SMS2 Inhibitor

SMS2-IN-3 is a potent and selective inhibitor of sphingomyelin synthase 2 (SMS2) with an IC50 of 2.2 nM. This compound significantly reduces hepatic sphingomyelin (22:0) levels, making it a valuable tool for research into sphingolipid metabolism and its implications in various metabolic disorders. SMS2-IN-3 is applicable in studies exploring the role of sphingolipids in health and disease.

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Biological Activity

Description	SMS2-IN-3 is a potent and selective inhibitor of sphingomyelin synthase 2 (SMS2) with an IC50 of 2.2 nM. This compound significantly reduces hepatic sphingomyelin (22:0) levels, making it a valuable tool for research into sphingolipid metabolism and its implications in various metabolic disorders. SMS2-IN-3 is applicable in studies exploring the role of sphingolipids in health and disease.

Product Information

Catalog Num	A77186
Formula	C33H39F3N4O6
Molecular Weight	644.68
CAS Number	2414240-89-2
SMILES	O=C(N1CCC(CCCOC(C2=C(N3C)N=CC=C2)=C(C(N(CC4=CC(OC)=CC(C(F)(F)F)=C4)C)=O)C3=O)CC1)OC5(CC5)C

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