Biological Activity
SMYD3-IN-1 (compound 29) is an irreversible and selective inhibitor of SMYD3 (SET and MYND domain containing 3), with an IC50 of 11.7 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.72 mL | 98.62 mL | 197.23 mL |
0.5 mM | 3.94 mL | 19.72 mL | 39.45 mL |
1 mM | 1.97 mL | 9.86 mL | 19.72 mL |
5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
*The above data is based on the productmolecular weight 507.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18572 |
---|---|
Actions | Inhibitor |
M. Wt | 507.02 |
Formula | C28H31ClN4O3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2095160-79-3 |
SMILES | O=C(N1[[email protected]](C)CN(C(C2=CC=C3C(Cl)=CC(C4=CC=C(C5(N)CC5)C=C4)=NC3=C2)=O)CC1)OCCC |
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