SN 38

Catalog No.: A12011
DNA topoisomerase Inhibitor
SN 38 is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor).
Grouped product items
Product Name Price Stock Qty
SN 38 50mg
$60.00
In stock
SN 38 100mg
$80.00
In stock
SN 38 250mg
$160.00
In stock
SN 38 10mM * 1mL in DMSO
$85.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's SN 38 has been cited by 5 publications
  • Akari Shiraishi, .et al. , Biochem Biophys Res Commun, 2024, Jun 11:725:150255 PMID: 38897043
  • Sarigama Rajesh, .et al. , Pharmaceutics, 2022, Oct 12;14(10):2175 PMID: 36297610
  • Chen JC, .et al. , Biomolecules, 2019, Sep 9;9(9) PMID: 31505885
  • Alibolandi M, .et al. , Artif Cells Nanomed Biotechnol, 2018, May 27:1-12 PMID: 29806500
  • Bar-Zeev M, .et al. , Eur J Pharm Biopharm, 2018, Dec;133:240-249 PMID: 30367935
  • Biological Activity
    Discription SN 38 is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor).
    Targets
    Target Value
    Product Information
    Catalog Num A12011
    Formula C22H20N2O5
    Molecular Weight 392.4
    CAS Number 86639-52-3
    SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)O
    Synonyms 7-Ethyl-10-hydroxycamptothecin, SN38, SN-38
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 20 mg/mL (50.96 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.48 mL 127.42 mL 254.84 mL
    0.5 mM 5.1 mL 25.48 mL 50.97 mL
    1 mM 2.55 mL 12.74 mL 25.48 mL
    5 mM 0.51 mL 2.55 mL 5.1 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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