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SNIPER(ABL)-024

Catalog No.: A19607
SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM.
SNIPER(ABL)-024
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Product Name Price Stock Qty
SNIPER(ABL)-024 1mg
$320.00
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SNIPER(ABL)-024 5mg
$960.00
In stock
SNIPER(ABL)-024 10mg
$1,600.00
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Biological Activity
Discription SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5μM.
Product Information
Catalog Num A19607
Formula C52H61F3N8O9S
Molecular Weight 1031.15
CAS Number 2222355-77-1
SMILES O=C(NCCOCCOCCOCCOC1=CC(C(C2=CSC([C@H]3N(C([C@H](C4CCCCC4)NC([C@H](C)NC)=O)=O)CCC3)=N2)=O)=CC=C1)C5=CC=CC(C6=NC=NC(NC7=CC=C(OC(F)(F)F)C=C7)=C6)=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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Angiogenesis > Bcr-Abl
PROTACs > SNIPERs
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