Sodium-binding benzofuran isophthalate

Catalog No.: A45385
Fluorescent Dye
Sodium-binding benzofuran isophthalate (SBFI) is a cell-impermeant fluorescent dye primarily used for the detection of sodium ions (Na+). Excitable at 340 nm, SBFI emits fluorescence at 450 nm, allowing for sensitive detection of sodium concentrations in biological samples. This compound exhibits selectivity for Na+ over potassium ions (K+), with dissociation constants (Kd) of 20 mM and 120 mM, respectively. SBFI is valuable for research applications involving ion transport and signaling in cellular environments.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSodium-binding benzofuran isophthalate (SBFI) is a cell-impermeant fluorescent dye primarily used for the detection of sodium ions (Na+). Excitable at 340 nm, SBFI emits fluorescence at 450 nm, allowing for sensitive detection of sodium concentrations in biological samples. This compound exhibits selectivity for Na+ over potassium ions (K+), with dissociation constants (Kd) of 20 mM and 120 mM, respectively. SBFI is valuable for research applications involving ion transport and signaling in cellular environments.
Product Information
Catalog NumA45385
FormulaC44H42N2O15
Molecular Weight838.81
CAS Number124549-08-2
SMILESO=C(C1=CC=C(C(C(O)=O)=C1)C2=CC3=CC(OC)=C(N4CCOCCOCCN(CCOCC4)C5=C(OC)C=C6C=C(C7=CC=C(C(O)=O)C=C7C(O)=O)OC6=C5)C=C3O2)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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