SSR126768A free base is a potent oxytocin receptor antagonist with a Ki of 0.44 nM. This compound acts as a tocolytic agent by inhibiting oxytocin-induced intracellular calcium signaling and prostaglandin release in human uterine smooth muscle cells. As a result, SSR126768A effectively inhibits oxytocin-induced uterine contractions and has been shown to delay parturition in pregnant rats experiencing labor. This reagent is valuable for research applications focused on reproductive biology and the modulation of uterine contractility.
SSR126768A free base is a potent oxytocin receptor antagonist with a Ki of 0.44 nM. This compound acts as a tocolytic agent by inhibiting oxytocin-induced intracellular calcium signaling and prostaglandin release in human uterine smooth muscle cells. As a result, SSR126768A effectively inhibits oxytocin-induced uterine contractions and has been shown to delay parturition in pregnant rats experiencing labor. This reagent is valuable for research applications focused on reproductive biology and the modulation of uterine contractility.
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