STF 118804

Catalog No.: A14072

NAMPT inhibitor

STF 118804

STF 118804 Chemical Structure

CAS NO. 894187-61-2

STF 118804 is a highly specific NAMPT inhibitor that reduces the viability of most B-ALL cell lines with high potency IC50 values in the low nanomolar range and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $110.00

Special Price $88.00

25 mg

Regular Price: $220.00

Special Price $176.00

50 mg

Regular Price: $380.00

Special Price $304.00

10mM * 1mL in DMSO

Regular Price: $85.00

Special Price $68.00

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Biological Activity

STF 118804 is a highly specific NAMPT inhibitor that reduces the viability of most B-ALL cell lines with high potency IC50 values in the low nanomolar range and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.
Targets
NAMPT
In vitro DMSO 53 mg/mL (114.83 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.34 mL 216.67 mL
0.5 mM 4.33 mL 21.67 mL 43.33 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14072
Actions Inhibitor
CAS No. 894187-61-2
Formula C25H23N3O4S
M. Wt 461.53
Purity >98%
Synonyms STF118804, STF-118804
SMILES CC1=CC=C(C=C1)S(=O)(=O)CC2=C(OC(=N2)C3=CC=C(C=C3)C(=O)NCC4=CN=CC=C4)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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