SU-5402 Chemical Structure

CAS NO. 215543-92-3

SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively).

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$200.00
50 mg
$350.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively).
Targets
VEGFR2 FGFR1 PDGFRβ
20 nM30 nM510 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.75 mL 168.74 mL 337.47 mL
0.5 mM 6.75 mL 33.75 mL 67.49 mL
1 mM 3.37 mL 16.87 mL 33.75 mL
5 mM 0.67 mL 3.37 mL 6.75 mL

*The above data is based on the productmolecular weight 296.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11558
Actions Inhibitor
M. Wt 296.32
Formula C17H16N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 215543-92-3
Synonyms SU5402, SU 5402
SMILES CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O

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