SW033291

Catalog No.: A15798

15-PGDH enzyme inhibitor

SW033291

SW033291 Chemical Structure

CAS NO. 459147-39-8

SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.

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Package Price Qty
5 mg
$75.00
10 mg
$120.00
25 mg
$270.00
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Biological Activity

SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.
Targets
15-PGDH 15-PGDH
0.1 nM(Ki)1.5 nM
In vitro (25°C) DMSO 77 mg/mL (186.62 mM)
Water Insoluble
Ethanol Warmed: 30 mg/mL (72.7 mM)
In vivo 5% DMSO+corn oil 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.24 mL 121.19 mL 242.37 mL
0.5 mM 4.85 mL 24.24 mL 48.47 mL
1 mM 2.42 mL 12.12 mL 24.24 mL
5 mM 0.48 mL 2.42 mL 4.85 mL

*The above data is based on the productmolecular weight 412.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15798
Actions Inhibitor
CAS No. 459147-39-8
Formula C21H20N2OS3
M. Wt 412.59
Purity >98%
Synonyms SW 033291, SW-033291
SMILES NC1=C(S(CCCC)=O)SC2=NC(C3=CC=CS3)=CC(C4=CC=CC=C4)=C21
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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