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Biological Activity
SY-1365 is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.03 mL | 85.16 mL | 170.32 mL |
| 0.5 mM | 3.41 mL | 17.03 mL | 34.06 mL |
| 1 mM | 1.7 mL | 8.52 mL | 17.03 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.41 mL |
*The above data is based on the productmolecular weight 587.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18482 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1816989-16-8 |
| Formula | C31H35ClN8O2 |
| M. Wt | 587.12 |
| Purity | >98% |
| Synonyms | SY1365, SY 1365 |
| SMILES | O=C(C1=NC=C(NC(/C=C/CN(C)C)=O)C=C1)N[[email protected]@]2(C)CCC[[email protected]@H](NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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