SY-1365

Catalog No.: A18482

CDK7 inhibitor

SY-1365

SY-1365 Chemical Structure

CAS NO. 1816989-16-8

SY-1365 is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

SY-1365 is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.03 mL 85.16 mL 170.32 mL
0.5 mM 3.41 mL 17.03 mL 34.06 mL
1 mM 1.7 mL 8.52 mL 17.03 mL
5 mM 0.34 mL 1.7 mL 3.41 mL

*The above data is based on the productmolecular weight 587.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18482
Actions Inhibitor
CAS No. 1816989-16-8
Formula C31H35ClN8O2
M. Wt 587.12
Solubility DMSO
Purity >98%
Synonyms SY1365, SY 1365
SMILES O=C(C1=NC=C(NC(/C=C/CN(C)C)=O)C=C1)N[[email protected]@]2(C)CCC[[email protected]@H](NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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