SYAF080 is a selective antagonist of the human A₂B adenosine receptor (hA₂B AdoR), exhibiting a binding affinity with a Ki of 23.6 nM and a KB of 25.2 nM. This compound does not exhibit inhibition of human CYP450 cytochromes, making it suitable for pharmacological studies. SYAF080 is valuable for research focused on inflammation, metabolic disorders, and cardiovascular diseases, providing insights into the therapeutic potential of A₂B receptor modulation.
SYAF080 is a selective antagonist of the human A₂B adenosine receptor (hA₂B AdoR), exhibiting a binding affinity with a Ki of 23.6 nM and a KB of 25.2 nM. This compound does not exhibit inhibition of human CYP450 cytochromes, making it suitable for pharmacological studies. SYAF080 is valuable for research focused on inflammation, metabolic disorders, and cardiovascular diseases, providing insights into the therapeutic potential of A₂B receptor modulation.
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