SYK-1106 is a highly potent delta-opioid receptor (DOR) agonist, exhibiting an EC50 of 89 pM and a Ki of 848 pM. This compound demonstrates selectivity for μ and κ opioid receptors, with Ki values of 9.54 nM and 2.45 nM, respectively. SYK-1106 has been shown to induce dose-dependent antidepressant-like effects, making it a valuable tool for research in the field of depression and related disorders.
SYK-1106 is a highly potent delta-opioid receptor (DOR) agonist, exhibiting an EC50 of 89 pM and a Ki of 848 pM. This compound demonstrates selectivity for μ and κ opioid receptors, with Ki values of 9.54 nM and 2.45 nM, respectively. SYK-1106 has been shown to induce dose-dependent antidepressant-like effects, making it a valuable tool for research in the field of depression and related disorders.
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