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T-1032

Catalog No.: A42025
PDE5 Inhibitor
T-1032 is a selective phosphodiesterase 5 (PDE5) inhibitor, exhibiting an IC50 value of 1.0 nM. This compound demonstrates a relaxant effect on isolated rabbit corpus cavernosum, making it a valuable tool for investigating mechanisms involved in erectile dysfunction. T-1032 is suitable for research applications focused on penile vascular physiology and therapies for erectile dysfunction.
T-1032 212500-03-3 PDE5 Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionT-1032 is a selective phosphodiesterase 5 (PDE5) inhibitor, exhibiting an IC50 value of 1.0 nM. This compound demonstrates a relaxant effect on isolated rabbit corpus cavernosum, making it a valuable tool for investigating mechanisms involved in erectile dysfunction. T-1032 is suitable for research applications focused on penile vascular physiology and therapies for erectile dysfunction.
Product Information
Catalog NumA42025
FormulaC32H31N3O11S
Molecular Weight665.67
CAS Number212500-03-3
SMILESOS(O)(=O)=O.NC1=CC=C(N2C(C(OC)=O)=C(C3=CC(OC)=C(C(OC)=C3)OC)C4=C(C=C(C=C4)OCC5=NC=CC=C5)C2=O)C=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Metabolism > PDE