T-10418

Catalog No.: A60446
G2A/GPR132 Agonist
T-10418 is a potent and selective agonist of the G2A/GPR132 receptor, exhibiting an EC50 of 0.82 μM for human G2A activation. This compound demonstrates favorable water solubility, metabolic stability, and pharmacokinetic properties, making it suitable for in vitro and in vivo studies. T-10418 is valuable for research into various medical conditions, including neuropathic pain, acute myeloid leukemia, and inflammation.
Grouped product items
Size Price Stock Qty
1mg
$115.00
In stock
5mg
$290.00
In stock
10mg
$480.00
In stock
25mg
$990.00
In stock
50mg
$1,330.00
In stock
100mg
$1,745.00
In stock
200mg
$2,285.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionT-10418 is a potent and selective agonist of the G2A/GPR132 receptor, exhibiting an EC50 of 0.82 μM for human G2A activation. This compound demonstrates favorable water solubility, metabolic stability, and pharmacokinetic properties, making it suitable for in vitro and in vivo studies. T-10418 is valuable for research into various medical conditions, including neuropathic pain, acute myeloid leukemia, and inflammation.
Product Information
Catalog NumA60446
FormulaC22H20N2O4
Molecular Weight376.41
CAS Number1608784-68-4
SMILESO=C(C1=CC(OCC2=CN=CC=C2)=CC=C1)N[C@H](CC3=CC=CC=C3)C(O)=O
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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